histamine to be released. Histamine is the chemical that initiates the itching, sneezing, and swelling of a sudden reaction. Bromelain is a protein digesting enzyme that is added to enhance the absorption of quercetin into the body. Bromelain is widely used in sports medicine to combat the discomfort and swelling of bruises, sprains, and muscle tears. One study conducted by an orthopedic surgeon showed that administering bromelain to 59 of his patients resulted in a clear reduction in both swelling and discomfort.* *Source: Food Chem Toxicol. 1995;33(12): 2061-1080.  (less)